Find 3,636 hotels in San Diego Santa Fe Depot
Hotels from €90
Choose from over 1,000,000 unique hotels, apartments & villas around the world
Get the best price available with ebookers Price GuaranteeOpens in a new window
Free cancellation on most hotels when you book with ebookers!*
Check availability on hotels close to San Diego Santa Fe Depot
Tomorrow night
Check prices close to San Diego Santa Fe Depot for tomorrow night, 20 Feb - 21 FebMost frequently booked hotels in San Diego Santa Fe Depot

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
8.46 km from San Diego Santa Fe Depot
The price is €161 per night
€161
includes taxes & fees
23 Feb - 24 Feb
The Dana on Mission Bay's great beach location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. You'll find features such as free WiFi in public areas, plus 2 outdoor pools and 2 poolside bars. This property offers pet-friendly amenities, such as food and water bowls.

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
0.42 km from San Diego Santa Fe Depot
The price is €173 per night
€173
includes taxes & fees
6 Mar - 7 Mar
The sightseeing around Wyndham San Diego Bayside gets high marks from our customers. During your stay, you're just a quick walk from USS Midway Museum. Enjoy features like a free round-trip airport shuttle, plus 2 restaurants and an outdoor pool.
Pool
Free airport shuttle

Omni San Diego Hotel
675 L St, San Diego, CA
1.4 km from San Diego Santa Fe Depot
The price is €230 per night
€230
includes taxes & fees
14 Mar - 15 Mar
Our customers tell us they can't get enough of Omni San Diego Hotel's great location. During your stay, you'll be connected to the convention centre and just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus an outdoor pool and a 24-hour gym.
Pool
Hot tub

Hard Rock Hotel San Diego
207 5th Ave, San Diego, CA
1.3 km from San Diego Santa Fe Depot
The price is €234 per night
€234
includes taxes & fees
16 Mar - 17 Mar
Our customers tell us they can't get enough of Hard Rock Hotel San Diego's great location. During your stay, you're just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 restaurants and 2 coffee shops/cafes.
Pool
Free WiFi

Hyatt Regency Mission Bay Spa and Marina
1441 Quivira Rd, San Diego, CA
8.64 km from San Diego Santa Fe Depot
The price is €224 per night
€224
includes taxes & fees
23 Feb - 24 Feb
Hyatt Regency Mission Bay Spa and Marina's great location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. Enjoy features like free WiFi in public areas, plus 3 outdoor pools and 2 restaurants. This property offers pet-friendly amenities, such as food and water bowls.
Pool
Hot tub

Comfort Inn Sea World Area
3880 Greenwood St, San Diego, CA
5.53 km from San Diego Santa Fe Depot
The price is €102 per night
€102
includes taxes & fees
24 Feb - 25 Feb
Our customers tell us that they can't get enough of the free breakfast at Comfort Inn Sea World Area. During your stay, you're just a quick walk from Pechanga Arena. You'll find features such as free WiFi in public areas and free self-parking, plus a gym.
Breakfast included
Pet-friendly

Sheraton Mission Valley San Diego Hotel
1433 Camino Del Rio S, San Diego, CA
5.7 km from San Diego Santa Fe Depot
The price is €127 per night
€127
includes taxes & fees
2 Mar - 3 Mar
The shopping around Sheraton Mission Valley San Diego Hotel gets high marks from our customers. During your stay, you'll be within walking distance of Mission Valley Mall. Free WiFi in public areas, an outdoor pool and a restaurant are available. This property offers pet-friendly amenities, such as food and water bowls.
Pool
Hot tub

Handlery Hotel
950 Hotel Cir N, San Diego, CA
4.92 km from San Diego Santa Fe Depot
The price is €111 per night
€111
includes taxes & fees
23 Feb - 24 Feb
Our customers tell us they can't get enough of Handlery Hotel's great location. During your stay, you'll be within walking distance of Fashion Valley Mall. Features include free WiFi in public areas, plus 2 restaurants and 2 bars.

Humphreys Half Moon Inn
2303 Shelter Island Dr, San Diego, CA
5.1 km from San Diego Santa Fe Depot
The price is €183 per night
€183
includes taxes & fees
2 Mar - 3 Mar
Humphreys Half Moon Inn's great location gets high marks from our customers. During your stay, you're just a quick walk from San Diego Bay. Enjoy features like an outdoor pool, a restaurant and a marina.
Pool
Hot tub

Sheraton San Diego Resort
1380 Harbor Island Dr, San Diego, CA
2.94 km from San Diego Santa Fe Depot
The price is €221 per night
€221
includes taxes & fees
7 Mar - 8 Mar
Our customers tell us they can't get enough of Sheraton San Diego Resort's great location. During your stay, you're just a quick walk from San Diego Bay. You'll find features such as a free round-trip airport shuttle, plus 3 outdoor pools and 6 restaurants. This property offers pet-friendly amenities, such as food and water bowls.

Lafayette Hotel & Club
2223 El Cajon Blvd, San Diego, CA
5.06 km from San Diego Santa Fe Depot
The price is €221 per night
€221
includes taxes & fees
23 Feb - 24 Feb
Our customers tell us that they can't get enough of the helpful staff at Lafayette Hotel & Club. During your stay, you'll be close to San Diego Zoo. Enjoy features like free WiFi in public areas, plus 2 restaurants and 3 bars.
Pool
Pet-friendly

Kings Inn San Diego
1333 Hotel Cir S, San Diego, CA
4.74 km from San Diego Santa Fe Depot
The price is €90 per night
€90
includes taxes & fees
25 Feb - 26 Feb
Our customers tell us they can't get enough of Kings Inn San Diego's great location. During your stay, you'll be within walking distance of Riverwalk Golf Club. Features include free WiFi in public areas, plus 2 restaurants and an outdoor pool.
Pool
Hot tub

The Sofia Hotel
150 W Broadway, San Diego, CA
0.45 km from San Diego Santa Fe Depot
The price is €201 per night
€201
includes taxes & fees
3 Mar - 4 Mar
Our customers tell us that they can't get enough of the helpful staff at The Sofia Hotel. During your stay, you're just a quick walk from San Diego Civic Theatre. Free WiFi in public areas, a full-service spa and a restaurant are available. This property offers pet-friendly amenities, such as food and water bowls.
Spa
Pet-friendly

The Horton Grand, Downtown/Gaslamp Quarter
311 Island Ave, San Diego, CA
0.98 km from San Diego Santa Fe Depot
The price is €179 per night
€179
includes taxes & fees
23 Feb - 24 Feb
Our customers tell us that they can't get enough of the comfortable beds at The Horton Grand, Downtown/Gaslamp Quarter. During your stay, you're just a quick walk from Petco Park. Enjoy features like a restaurant, a gym and a bar.
Pet-friendly
Restaurant

Bay Club Hotel & Marina
2131 Shelter Island Dr, San Diego, CA
5.18 km from San Diego Santa Fe Depot
The price is €142 per night
€142
includes taxes & fees
6 Mar - 7 Mar
Our customers tell us they can't get enough of Bay Club Hotel & Marina's great location. During your stay, you're just a quick walk from San Diego Bay. You'll find features such as free WiFi in public areas, plus an outdoor pool and a restaurant.
Pool
Hot tub
Don't see what you're looking for?
See all available properties in San Diego Santa Fe Depot
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
San Diego Santa Fe Depot hotels essential information
Accommodation | 3,636 hotels |
---|---|
Lowest Price | €90 |
Highest Price | €234 |
Popular hotels | The Dana on Mission Bay, Wyndham San Diego Bayside, Omni San Diego Hotel, Hard Rock Hotel San Diego, Hyatt Regency Mission Bay Spa and Marina, Comfort Inn Sea World Area, Sheraton Mission Valley San Diego Hotel, Handlery Hotel, Humphreys Half Moon Inn, Sheraton San Diego Resort, Lafayette Hotel & Club, Kings Inn San Diego, The Sofia Hotel, The Horton Grand, Downtown/Gaslamp Quarter, Bay Club Hotel & Marina |
Recently booked San Diego Santa Fe Depot hotelsebookers verified reviews

Hard Rock Hotel San Diego
5/5 Excellent
"Second time staying at the Hard Rock and it was a great visit once again. Everything exceeded my expectations. "
A verified traveller stayed at Hard Rock Hotel San Diego
Posted 2 days ago
Areas of San Diego Santa Fe Depot
Hotels by...
Other accommodation options
Top Trending
Hotels
Cheap Hotels in HolywoodGrange Castle Golf Club hotelsHostels RolleResort World Sentosa Casino hotelsCheap Hotels in OtleySiri Fort Sports Complex hotelsVillas County CorkCheap Hotels in WhitegateHotels in CastlereaghCheap Hotels in TenerifeCheap Hotels in RixensartHostels Amsterdam Sloterdijk StationB&B LucanCottages BalbrigganChalets SestriereCheap Hotels in ArdrahanB&B BanteerApartments Maynooth
Flights
Holiday Rentals